PSX 2020: On the Hunt for Emerging Chemicals of Concern

PSX 2020: On the Hunt for Emerging Chemicals of Concern

PSX 2020: On the Hunt for Emerging Chemicals of Concern 150 150 Meghan Dengler

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Presentation: On the Hunt for Emerging Chemicals of Concern
When: September 16th, 2020 at 1:30pm-3pm EST
Presenter(s): Ari Lewis, Gradient; Dr. Adam Grossman, PraedicatDr. Patrick McMullen, ScitoVation

Adam Grossman, Sr. Scientist and VP of Modeling at Praedicat, is presenting during the Product Stewardship Conference (PSX) 2020 virtual event on Wednesday, September 16th at 1:30pm (EST).  During this session: “On the Hunt for Emerging Chemicals of Concern,” Dr. Grossman will be joined by Ari Lewis and Dr. Patrick McMullen to discuss the different approaches, and emerging tools, that support the identification and evaluation of potential chemicals of concern and the “toxicity surprises” on the horizon.

To sign up to attend the event register here.

Read more about Dr. Grossman’s presentation here.

To learn about how predictive data and available tools such as Praedicat’s ChemMeta® can help your company, click here.



Presentation Description

Amid heightened public awareness, increased regulatory scrutiny, and the constant threat of legal action, it is important for companies to be aware of the toxicity of the chemicals they market, even chemicals that have been used for decades. Failing to proactively manage a chemical portfolio may lead to unexpected “toxicity surprises” that can cause business disruptions and product liability claims. The data and tools available to assess chemical toxicity are rapidly growing. The expanded insight into chemical toxicity stems from increased access to publicly available peer-reviewed resources, extensive animal testing data through regulatory programs (e.g., REACH, Tox21/ToxCast), and innovative in vitro and in silico methods. These data serve as leading indicators of chemicals that may present medium- and long-term toxicity risks and become tomorrow’s substances of concern.

The goal of this session is to provide an overview of different approaches that support the identification and evaluation of potential chemicals of concern in the near term (1-3 years) and to explore tools that will promote the proactive selection of more sustainable materials in the long term (3+ years).

Learning Objectives

By attending this deep-dive session, attendees will learn the importance of:

  • Using available in vitro, in silico, and genomics approaches to predict potentially toxic chemicals, particularly in material selection and development processes.
  • Understanding applicability of New Approach Methodologies (NAMs) for discovery prioritization, risk assessment, and regulatory submission support.
  • Analyzing data from government programs (e.g., REACH, Tox21/ToxCast) to understand chemical toxicity and support informed chemical substitutions well before they are declared hazardous.
  • Monitoring the peer-reviewed literature to assess today’s consensus and to predict which chemicals and substances are likely to attract more attention from the scientific community, regulatory agencies, and the public.
  • Integrating information to make informed decisions about ingredient selection and development that mitigate business risk.

Learning/Experience Level: Competent

Future Products Considerations: Predictive Tools